J Herbmed Pharmacol. 2016;5(4):125-130.
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Review

Haplophyllum tuberculatum: An overview

Abdolshakoor Raissi 1 * , Mina Arbabi 2, Javad Roustakhiz 3, Masih Hosseini 4

1 Faculty of agriculture, Department of Horticulture, Velayat University, Iranshahr, Iran
2 PhD Student of Medicinal Plant, Islamic Azad University, Science and Research Branch, Tehran, Iran
3 Higher Educational Complex of Saravan, Saravan University, Saravan, Iran
4 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

Abstract

Introduction: Haplophyllum tuberculatum, belonging to the Rutaceae family, is distributed in south-eastern regions of Iran, particularly in Baloochestan. This study was aimed to investigate and collect scientific reports such as morphological characteristics, phytochemical compounds, ecology, biotechnology and evaluation of the therapeutic properties of this valuable medicinal plant.Methods: In order to gather the information the keywords Haplophyllum tuberculatum, botany, genetic, biotechnology, therapeutic, and pharmacology were searched until 2016 from journals accessible in databases such as Scopus, EBSCO, Science Direct, Medline, PubMed, Embase, SID and Iran Medex.Results: The results in this study revealed various pharmacological properties including anti-cancer, antioxidantant, uterus-relaxing, anti-bacterial and anti-HIV activities for this plant which are probably due to the presence of aromatic compounds such as two alkaloids named haplophytin-a and B, and essential oils.Conclusion: Haplophyllum tuberculatum possesses various pharmacological properties and the bioactive molecules of this plant play an important role in human health, hence, it might be used for different drug productions.

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Revised: 25 Aug 2016
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