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J Herbmed Pharmacol. 2015;4(2): 45-48.
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Original Article

Antibacterial effects of Solanum tuberosum peel ethanol extract in vitro

Raana Amanpour 1, Saeid Abbasi-Maleki 2*, Moslem Neyriz-Naghadehi 3, Majid Asadi-Samani 4

1 Department of Microbiology, Urmia Branch, Islamic Azad University, Urmia, Iran
2 Department of Pharmacology, Urmia Branch, Islamic Azad University, Urmia, Iran
3 Department of Food Hygiene, Urmia Branch, Islamic Azad University, Urmia, Iran
4 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding author: Dr. Saeid Abbasi-Maleki, Department of Pharmacology, Urmia Branch, Islamic Azad University, Urmia, Iran, dr.s.a.maleki@gmail.com

Abstract

Introduction: Today, medicinal plants are being widely used due to being natural, available, and cheaper than synthetic drugs and having minimum side effects. Since there were reports about the antibacterial properties of Solanum tuberosum (SE), the aim of this study was to investigate the antibacterial effects of SE ethanol extract in vitro condition on Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae

Methods: Ethanol extract of SE peel was prepared by maceration method. Initially, antibacterial activity of ethanol extract of SE was qualitatively determined by disk diffusion test; then, the minimum inhibitory concentration and minimum bactericidal concentration were qualitatively determined by micro-dilution method.

Results: SE peel extract had antibacterial properties and its effect was more pronounced on gram-positive bacteria, especially S. aureus (0.62±0.00 mg/ml). The extract had antibacterial activity on gram-negative bacteria, P. aeruginosa, too (8.33±2.88 mg/ml).

Conclusion: SE peel extract has antibacterial activity and its effect on gram-positive bacteria was more pronounced than the investigated gram-negative bacteria. Therefore, it is suggested that SE peel constituent compounds be determined and to determine the exact mechanism of its antibacterial properties, and more comprehensive research be done to apply it, clinically.

Keywords: Solanum tuberosum, Ethanol extract, Antibacterial activity, In vitro condition

Implication for health policy/practice/research/medical education:

Solanum tuberosum peel ethanol extract has good antibacterial properties against gram-positive bacteria. Nevertheless, more investigations need for identification of the active chemical constituents of SE peel ethanol extract responsible for its antibacterial properties as well as their specific mechanisms of action.

Please cite this paper as: Amanpour R, Abbasi-Maleki S, Neyriz-Naghadehi M, Asadi-Samani M. Antibacterial effects of Solanum tuberosum peel ethanol extract in vitro. J Herbmed Pharmacol. 2015; 4(2): 45-48.

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