Shahrekord University of Medical Sciences Journal of Herbmed Pharmacology 2345-5004 10 1 2021 01 01 Mallotus philippensis (Lam.) Müll. Arg.: A review on its pharmacology and phytochemistry 31 50 10.34172/jhp.2021.03 EN Abhishek Kumar https://orcid.org/0000-0003-2252-7623 Meenu Patil https://orcid.org/0000-0002-7664-7877 Pardeep Kumar https://orcid.org/0000-0001-6707-1485 Ram Chand Bhatti https://orcid.org/0000-0002-0975-9641 Rupinder Kaur https://orcid.org/0000-0002-1986-5544 Nitin Kumar Sharma https://orcid.org/0000-0002-1371-8076 Anand Narain Singh https://orcid.org/0000-0002-0148-8680 Journal Article 10.34172/jhp.2021.03 2019 09 21 2019 11 04 Kamala tree (Mallotus philippensis) is traditionally used by different ethnic groups to treat a variety of diseases and health ailments. However, these traditional uses need to be scientifically investigated and validated in order to develop drugs from this tree. Therefore, the present article is aimed to review the scientifically validated knowledge on the pharmacology and phytochemistry of the tree. To accomplish this, we extensively surveyed the available databases like Scopus, Web of Science, Google Scholar, ScienceDirect, NCBI including PubMed and PubChem, etc. by using keywords ‘Mallotus philippensis’, ‘Mallotus phillippinensis’ and ‘Mallotus philippinensis’. Our results indicated that the tree possesses more than 50 different types of important phytochemicals of natural origin. The wide array of phytochemicals possesses fascinating biological activities like anthelmintic, antibacterial, anti-inflammatory, anti-oxidant, anti-cancerous, anti-tuberculosis, anti-parasitic, analgesic, anti-urolithiatic and anti-viral activities. Thus, pharmacological activities and isolation of active phytochemicals make the tree a promising candidate for drug discovery. However, pharmacological activities such as antibacterial and anti-oxidant activities are often tested with crude extracts and in vitro rudimentary methods that can be sometimes misleading and non-specific. Thus, more sophisticated techniques may be applied for the isolation of active chemicals and elucidating their mechanism of actions.