Shahrekord University of Medical Sciences Journal of Herbmed Pharmacology 2345-5004 13 2 2024 04 01 Therapeutic potential of fucoidan in dentistry: A review 188 198 10.34172/jhp.2024.48302 EN Maya Hudiyati https://orcid.org/0009-0007-3862-5523 Siti Sunarintyas https://orcid.org/0000-0003-2124-674X Retno Ardhani https://orcid.org/0000-0003-4995-6567 Alim Isnansetyo https://orcid.org/0000-0002-3219-1185 Journal Article 10.34172/jhp.2024.48302 2023 10 10 2023 12 07 Fucoidan, produced by the cell walls of brown seaweed, possesses biological effects, covering anticancer, antiviral, anti-inflammatory, antioxidant, and a potential for promoting angiogenesis and osteogenesis. This study aimed to compile diverse scientific results on fucoidan’s therapeutic prospect in dentistry and the mechanism of action in the therapy of oral diseases. A literature search was carried out using keywords with Boolean operators, including fucoidan (AND) oral (OR) dental (OR) dentistry, to identify related publications from PubMed, ScienceDirect, and Google Scholar databases. The results showed that fucoidan had various therapeutic potentials in the field of dentistry, including anticancer, anti-inflammatory, radioprotection, protection of dental pulp tissue, and bone regeneration. These characteristics were related to the sulfate composition and molecular weight. Fucoidan has various therapeutic potentials crucial for oral health. Hence, it might be used for material development and drug production in dentistry