Shahrekord University of Medical Sciences Journal of Herbmed Pharmacology 2345-5004 8 2 2019 03 15 A mini-review on phytochemistry and pharmacological activities of Scrophularia striata 85 89 10.15171/jhp.2019.14 EN Pari Tamri https://orcid.org/0000-0001-9553-415X Journal Article 10.15171/jhp.2019.14 2018 10 22 2019 01 24 Introduction: Scrophularia striata (Scrophulariaceae) is an important medicinal plant in Iran and in Iranian folk medicine it has been used for variety of disorders. The present article aims to provide a review at the studies done on phytochemistry and pharmacological effects of S. striata. Methods: This mini review is based on a literature study of scientific journals from electronic sources, such as Science Direct, PubMed, Google Scholar, Scopus and Web of Science. Results: The main chemical constituents which have been isolated and identified from Scrophularia striata are cinnamic acid, some flavonoids such as quercetin, isorhamnetin3-O-rutinoside and nepitrin and one glycoside (acteoside1) . This plant possesses antiinflammatory , antibacterial , antioxidant, anticancer, analgesic and neuroprotective effects. In addition it accelerates wound healing process Conclusion : Scrophularia striata has a potential for the treatment of several diseases and disorders, but there are only a few studies done to investigate the plant phytochemistry, thus f urther studies should be focused on isolation and identification of active compounds with pharmacological activities. Besides, the majority of pharmacological studies have been performed using aerial parts of plant , thus further studies are needed to investigate bioactivity of other parts of the plant.