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J Herbmed Pharmacol. 2012;1(1): 3-9.
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Review

A review study on medicinal plants affecting amnesia through cholinergic system

Azar Baradaran 1, Zahra Rabiei 2, Mortaza Rafieian 3, Hedayatollah Shirzad 2*

1 Department of Clinical Pathology, Isfahan University of Medical Sciences, Isfahan, Iran
2 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
3 Isfahan Governer Office, Isfahan, Iran
*Corresponding Author: *Corresponding author: Hedayatollah Shirzad, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran. , Email: shirzadeh@yahoo.com

Abstract

Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and rivastigmine are cholinesterase inhibitors which are widely used in the treatment of amnesia, however, their therapeutic effects are not significant. Therefore, other possibilities including herbal medicine sources have been considered for memory loss therapy. There are some Medicinal plants with cholinomimetic property which mostly possess antioxidant activity, too. These plants may not only ameliorate amnesia but also can be a good source for drug discovery. In this paper other than introducing the medicinal plants and their components affective on cholinergic system and effective on memory loss, their probable advantages over synthetic drugs are discussed.

Implication for health policy/practice/research/medical education:

Getting familiar with medicinal plants effective on amnesia to make it easy choosing a suitable one for prevention or amelioration of amnesia.

Please cite this paper as: Baradaran A, Rabiei Z, Rafieian M, Shirzad H. A review study on medicinal plants affecting amnesia through cholinergic system. J Herbmed Plarmacol. 2012; 1(1): 3-9.

 

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ePublished: 01 Dec 2012
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