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J Herbmed Pharmacol. 2013;2(1): 1-3.
  Abstract View: 3763
  PDF Download: 2452

Original Article

A comparison study on the anti-leech effects of onion (Allium cepa L) and ginger (Zingiber officinale) with levamisole and triclabendazole

Mahmoud Bahmani 1*, Naiema Vakili-Saatloo 2, Majid Gholami-Ahangaran 3, Seyed Ahmad Karamati 4, Ebrahimkhalil Banihabib 1,5, Ghader Hajigholizadeh 1, Sayfollah Borjian 6

1 Food and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran
2 Department of Food Safety, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran
3 Department of Poultry Diseases, Veterinary Medicine Faculty, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran
4 Department of Parasitology and Mycology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
5 Faculty of Traditional Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
6 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding Author: *Corresponding author: Dr. Mahmoud Bahmani; Food and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran. , Email: mahmood.bahmani@gmail.com

Abstract

Introduction: Leech may indwell in mucosa of the pharynx, tonsil, esophagus, nose, nasopharyngeal and rarely in larynx of hosts, however, the effective drugs against this parasite is scarce. This study was aimed to evaluate and compare the anti-leech effect of methanolic extract of onion (Allium cepa L) and ginger (Zingiber officinale) with levamisole and triclabendazole.

Materials and Methods: In this study, 60 leeches (Limnatis nilotica) were collected from south of Ilam. The anti-leech effect of methanolic extract of onion and ginger in comparison with levamisole and triclabendazole drugs (positive controls) were evaluated. Distilled water was used as negative control. Paralysis and death of leeches were recorded in 720 minutes.

Results: Lethal effect of methanolic extract of ginger against Limnatis nilotica was equal to levamisole and more than triclabendazole and methanolic extract of onion.

Conclusion: Ginger equal to levamisole has anti-leech activity and its methanolic extract might be used against Limnatis nilotica.


Implication for health policy/practice/research/medical education:

Ginger has anti-leech activity equal to levamisole and its methanolic extract might be used against Limnatis nilotica.

Please cite this paper as: Bahmani M, Vakili-Saatloo N, Gholami-Ahangaran M, Karamati SA, Khalil-Banihabib E, Hajigholizadeh Gh, et al.A comparison study on the anti-leech effects of onion (Allium cepa L) and ginger (Zingiber officinale) with levamisole and triclabendazole. J Herbmed Pharmacol. 2013; 2(1): 1-3.

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ePublished: 01 Jun 2013
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