Logo-jhp
J Herbmed Pharmacol. 2014;3(1): 53-56.
  Abstract View: 3161
  PDF Download: 1642

Original Article

The effect of aqueous Elaeagnus angustifolia extract on acute non-inflammatory diarrhea in 1-5 year old children

Abofazl Khoshdel 1*, Fatemeh Famuri 2, Elham keivani 3, Masoud Lotfizadeh 2, Karam-Ali Kasiri 2, Mortaza Rafieian 4

1 Clinical Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
3 Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran
4 Isfahan Governor Office, Isfahan, Iran
*Corresponding Author: *Corresponding author: Abofazl Khoshdel,, Email: Nikakhosh@gmail.com

Abstract

Introduction: Acute diarrhea is one of the most important causes of global childhood mortality and morbidity. The most common complication of acute diarrhea is dehydration. The aim of this study was to evaluate the use of aqueous Elaeagnus angustifolia extract in controlling non-inflammatory diarrhea in a hospital setting.

Methods: In this case–controlled randomized double blind clinical trial 80 children in age range of 1-5 years were admitted in pediatric ward with diagnosis of non-inflammatory diarrhea. The patients were randomly divided into two equal groups of 40 cases. The subject in the first group received aqueous Elaeagnus angustifolia extract, 1.2 ml/Kg single dose for 4 days duration and the second group (control group) 1.2 cm/Kg distilled water single dose for 4 days duration. Data analysis were performed by Chi-square and t-tests, using SPSS software.

Results: The groups were similar regarding gender, mean age, and frequency, and consistency of defecation (p> 0.05). Although the children seemed better in regard to frequency and consistency of defecation, however the results showed that aqueous extract of Elaeagnus angustifolia was not significantly effective in the treatment of non-inflammatory diarrhea.

Conclusion: The results of this study demonstrated that the use of aqueous extract of Elaeagnus angustifolia was not effective in the treatment of non-inflammatory diarrhea in children.


Implication for health policy/practice/research/medical education:

The results of this study demonstrated that the use of aqueous extract of Elaeagnus angustifolia might not be significantly beneficial in the treatment of non-inflammatory diarrhea.

Please cite this paper as: Khoshdel A, Famuri F, Keivani E, Lotfizadeh M, Kasiri KA, Rafieian M. The effect of aqueous Elaeagnus angustifolia extract on acute non–inflammatory diarrhea in 1-5 year old children. J Herbmed Pharmacol. 2014; 3(1): 53-56.

First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 3162

Your browser does not support the canvas element.


PDF Download: 1642

Your browser does not support the canvas element.

ePublished: 01 Jun 2014
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)