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J Herbmed Pharmacol. 2018;7(2): 74-78. doi: 10.15171/jhp.2018.13

Original Article

Bioactivity guided isolation of apigenin from Stachys lavandulifolia Vahl. in mice with anxiolytic effects

Mohammad Rabbani 1, Seyed-Ebrahim Sajjadi 2, Masoumeh Karimi-Firozjai 1, Mostafa Ghannadian 2, 3 * ORCID

Cited by CrossRef: 8


1- Akbari-Ahangar A, Delnavazi M. Flavone Glycosides from the Aerial Parts of Stachys lavandulifolia Vahl. Pharm Sci. 2020;26(2):198 [Crossref]
2- Islam M, Zaman S, Biswas K, Al-Amin M, Hasan M, Alam A, Tanaka T, Sadik G. Evaluation of cholinesterase inhibitory and antioxidant activity of Wedelia chinensis and isolation of apigenin as an active compound. BMC Complement Med Ther. 2021;21(1) [Crossref]
3- Singh A, Upadhayay S, Mehan S. Inhibition of c-JNK/p38MAPK signaling pathway by Apigenin prevents neurobehavioral and neurochemical defects in ethidium bromide-induced experimental model of multiple sclerosis in rats: Evidence from CSF, blood plasma and brain samples. Phytomedicine Plus. 2021;1(4):100139 [Crossref]
4- Tomou E, Barda C, Skaltsa H. Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity. Medicines. 2020;7(10):63 [Crossref]
5- Dastan D, Dobie C, Zadali R, Pourrashid M, Skropeta D, Miran M. Botanical description, phytochemical constituents, ethnobotany, traditional medicinal use, and pharmacological activities of Stachys lavandulifolia Vahl . Natural Product Research. 2024;:1 [Crossref]
6- Eivani M, Miarkolae S, Ebrahimian J, Karimani F, Khoshnazar S. Melissa officinalis Interaction with Opioid Receptors Attenuates Stress-Induced Anxiety-Like and OCD-Like Behaviors. Biol Bull Russ Acad Sci. 2024;51(4):1113 [Crossref]
7- Bhardawaj H, Vasudeva N, Sharma S. Phytochemistry and Pharmacological Aspects of Apigenin: A Review. NPJ. 2023;13(4) [Crossref]
8- Bahadori M, Zengin G, Dinparast L, Eskandani M. The health benefits of three Hedgenettle herbal teas (Stachys byzantina, Stachys inflata, and Stachys lavandulifolia) - profiling phenolic and antioxidant activities. European Journal of Integrative Medicine. 2020;36:101134 [Crossref]
9- Jadidi A, Irannejad B, Salehi M, Safarabadi M. Effect of stachys lavandulifolia on occupational stress in emergency medical technicians. EXPLORE. 2023;19(6):803 [Crossref]