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J Herbmed Pharmacol. 2021;10(3): 331-338. doi: 10.34172/jhp.2021.38

Original Article

Establishment of long-term high-fat diet and low dose streptozotocin-induced experimental type-2 diabetes mellitus model of insulin resistance and evaluation of seed extracts of Syzygium cumini

Pratibha Nadig 1 * ORCID, Meharban Asanaliyar 1 ORCID, Kevin Manohar Salis 1 ORCID

Cited by CrossRef: 3


1- Sudirman S, Hwang Y, Su C, Lu T, Kuo H, Hwang D, Kong Z. Blue mussel (Mytilus edulis) water extract ameliorates intestinal immune response in high-fat diet–streptozotocin-induced diabetic mice. Food Funct. 2024;15(18):9357 [Crossref]
2- Bangar N, Dixit A, Apte M, Tupe R. Syzygium cumini (L.) skeels mitigate diabetic nephropathy by regulating Nrf2 pathway and mitocyhondrial dysfunction: In vitro and in vivo studies. Journal of Ethnopharmacology. 2025;336:118684 [Crossref]
3- Hassan A, Safuan S, Abdullah Z, Tan N. Cholic acid enhanced hypercholesterol parameters in high cholesterol diet fed Sprague-Dawley rats. Physiol Pharmacol. 2024;28(4):400 [Crossref]
4- Rizvi M, Rabail R, Munir S, Inam-Ur-Raheem M, Qayyum M, Kieliszek M, Hassoun A, Aadil R. Astounding Health Benefits of Jamun (Syzygium cumini) toward Metabolic Syndrome. Molecules. 2022;27(21):7184 [Crossref]
5- Mia M, Ahmed Q, Ferdosh S, Islam M, Samdani M, Sarker M. Antidiabetic potential of Phaleria macrocarpa fruit liquid COâ‚‚ extract: Bioactivity, cytotoxicity, phytochemicals and molecular targets. Phytomedicine Plus. 2025;5(3):100814 [Crossref]
6- Ajiboye B, Famusiwa C, Ojelabi A, Akinola W, Adeyemi E, Adejumo A, Owolabi O, Jeje T, Bamisaye F, Oyinloye- B, Vitalini S, Iriti M. Hibiscus sabdariffa Leaf Extract Activate Molecular Gene Expressions of Insulin and GLP-I Receptor in Streptozotocin-Induced Rats. Pharmacophore. 2024;15(5):15 [Crossref]
7- Ajiboye B, Famusiwa C, Oyedare D, Julius B, Adewole Z, Ojo O, Akindele A, Hosseinzadeh H, Brai B, Oyinloye B, Vitalini S, Iriti M. Hibiscus sabdariffa Leaf Extract Enhances Molecular Gene Expression of Insulin and GLP-1 Receptors in Streptozotocin-Induced Rats. Spec J Pharmacogn Phytochem Biotechnol. 2024;4(1):59 [Crossref]