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J Herbmed Pharmacol. 2024;13(3): 439-449. doi: 10.34172/jhp.2024.49420

Original Article

In vitro investigation of xanthine oxidase inhibitory and antioxidant activities of 3,4,5-trihydroxycinnamic acid

Taweesak Dhammaraj 1 * ORCID, Phoobet Kotseekieo 1 ORCID, Tunnathon Chotikarn 1 ORCID, Narumol Phosrithong 2 ORCID, Wattanakarn Praison 1 ORCID, Tossapol Prasomsub 1 ORCID, Panupong Lumthong 1 ORCID, Warangrat Supaporn 1 ORCID, Bunleu Sungthong 1,3 ORCID, Chawannuch Mudjupa 1,3 ORCID, Pawitra Pulbutr 1,3 ORCID

Cited by CrossRef: 2

1- Dhammaraj T, Lamlong C, Sriputthatham S, Saentaweesuk W, Wichai N. Total flavonoid and phenolic contents, xanthine oxidase inhibition, antioxidant and anti-inflammatory activities of ethanolic and aqueous extracts of the Ya-Tom-Kae-Ka-Sai-Sen remedy, a traditional Thai medicine. J Herbmed Pharmacol. 2025;14(4):504 [Crossref]
2- reda Kachmar M, Bouddine T, Ed-dra A, Kachmar S, Anarghou H, Alnasser S, Alshabrmi F, Al-Mijalli S, Abdallah E, Mrabti N, Laabar A, Chikhaoui M, Aziz G, Hajji L, Chakir S. Biological Potential and Chemical Characterization of Juniperus oxycedrus Leaves and Seed Cones. Phyton. 2025;94(3):657 [Crossref]
3- Hicham A, Amal B, Amina B, Said G. In silico study of the xanthine oxidase enzyme inhibition by the essential oil compounds of Myrtus communis plant in the treatment of gout disease. Reac Kinet Mech Cat. 2025;138(2):689 [Crossref]
4- Badaoui M, Mosbah A, Mokrani E, Rebbas K, Abdelkader M, Mokhtari M, Slimani A, Bensouici C, Yilmaz M, Cakir O, Tarhan A, Zengin G, Akkal S. Evaluation of the Phenolic Profile, Antioxidant, and Anti‐Gout Effects of Three Aerial Parts of the Algerian Herb Diplotaxis harra. Chemistry & Biodiversity. 2026;23(4) [Crossref]
5- Sahoo G, Nayak A, Gadnayak A, Dash B, Jena S, Ray A, Panda P, Nayak S, Sahoo A. Computer-aided screening of phytoconstituents from Plumeria species targeting xanthine oxidase inhibition: a combination of pharmacokinetics, molecular docking and molecular dynamics approaches. Computational Biology and Chemistry. 2025;119:108557 [Crossref]
6- Bellahcene F, Benarous K, Erol E, Serseg T, Topçu G, Linani A, Bouakkaz H, Kaouka A, Yousfi M. Phytochemical and Computational Discovery of Potent Xanthine Oxidase Inhibitors From Ziziphus lotus L. Leaves and Seeds. Chemistry & Biodiversity. 2026;23(1) [Crossref]

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